Pharmacological management of attention deficit hyperactivity disorder (ADHD) in adults is a topic that has gained significant attention in recent years. In this Australian Prescriber Podcast, Dr. Justin Coleman interviews Professor Shuichi Suetani about the pharmacological management of ADHD in adults. Professor Suetani, a fellow Queenslander and expert in the field, discusses the evolution of ADHD as a medical condition and the challenges of diagnosing and treating it in adults. One of the key points emphasized is the importance of a comprehensive assessment, considering both physical and mental health factors, as well as the impact of the environment on behavior. The interview also covers the various pharmacological options available for ADHD treatment, including psychostimulants and non-psychostimulants, and the cardiovascular risks associated with these medications. Professor Suetani provides practical advice for patients, emphasizing the need for a holistic approach to treatment and the importance of non-pharmacological interventions. Overall, the podcast offers a valuable insight into the complexities of managing ADHD in adults and the need for a tailored approach to treatment.